The first of the three publications describes a study by Jeanette Erdmann.
The MRAS gene on chromosome 3 is believed to play a role in the biology of blood vessels, while the gene on chromosome 12 is HNF1A probably involved in cholesterol metabolism. Both genes offer new opportunities for study by scientists in the underlying mechanisms of coronary heart disease are interested. – We started with Affymetrix 500K array in 2006 because the contents of the arrays was unique in 2007, we have seven new loci for myocardial infarction, 4 identified largely as a result of early access to these arrays for our Cardiogenics Consortium said Jeanette Erdmann molecular genetics molecular genetic laboratory at the Department of Cardiology at the University of L? beck and a member of the Consortium Cardiogenics.
New susceptibility locus for coronary artery disease on chromosome 3q22. Nature Genetics 41:280-282 .3 Press Release: The Wellcome Trust Case Control Consortium and Cardiogenics Identify Key Genes in Coronary Artery Disease with Affymetrix technology.4 Samani N. Genome wide association studies analysis of Coronary Artery Disease. England Journal of Medicine 357 :443-53 . Genome-wide haplotype association study identifies the SLC22A3 – LPAL2 – LPA gene cluster as a risk locus for coronary artery disease.Years people have Add a step that we see in the physical and chemical micro – environment of the cells, Chien. Now we are in optimum condition, to multiply is best for the cells , and seek differentiate. .. Recent Strategies for identification of the factor focusing HSC biology typically on any factor on more complex the complex cross-talk between the many components which on the cells. In combination so high-throughput cellular array technology of UCSD researchers systematic assesses and probe the complex relationship between hepatic stellate cells and components their microenvironment.
Technology works carried surrounds to control of various environments star-shaped hepatocytes as hepatic stellate cells . HSC are the principal cell type liver fibrosis, permit the formation up of scar tissue responsive to hepatic damage is involved. The enabled stellate cells be responsible for the secretion of collagen, which producing one fibrous scars to cirrhosis to cirrhosis.. And however IHSS program – hours have trimmed by 3.6 % January 2014, and she are continue on-the – cuts in of 8.4 per cent, targeted reduction of targeted reduction the Governor budgets Porn by Adult Days on Health for the elimination for disposal Supplemental Security Income cash payments are to be reduced on single low-income at the age and people with disabilities.
In this thesis the researchers have one array system, which use the biological elements that lead to and may identified to alleviate hepatic disease.