The primary efficacy endpoint of the study.

The primary efficacy endpoint of the study, the incidence of gastric ulcers during the 12-week study treatment period. The study will also evaluate secondary endpoints including incidence of duodenal ulcers, manner. Change in the number of ulcers and / or erosions of patient, time-to-onset analysis of ulcer and / or erosion development and the severity of the entire gastrointestinal injury by using a standardized grading scale. The study has registered a total of 124 patients with osteoarthritis and / or rheumatoid arthritis at 12 sites in the United States.

‘.. Cobiprostone in in two Phase 1 studies in healthy volunteers, and. In three Phase 2 studies including one study in patients with Raynaud’s disease, a study in patients with non – alcoholic fatty liver disease and in one study in patients with cystic fibrosis Sucampo Pharmaceuticals has the exclusive worldwide rights to develop and commercialize cobiprostone for all indications.

Sucampo closes enrollment in its Phase 2 Trial Of Cobiprostone for the prevention of NSAID-induced ulcersSucampo Pharmaceuticals, Inc.It is unclear higher, to survive benefit by physical activity in all domains of was always higher on women. Study authors suspect changes in the female hormone balance in the estrogen metabolism and distribution of body fat could in part responsible for this difference.. Studied and sports , early death risk by up to 40 % of.

Benefit women more than menin Europe, only a third of adult population , the minimum wHO recommendations to physical exercise. Improved physical activity been related to reduced all-cause mortality, independently of whether at work, leisure or active transport.

Meeting of the WHO recommended by level of 150 minutes a week moderate physical activity in everyday life or in leisure time were associated with decreased in mortality rates risk of ten per cent? On powerful physical activity and sport the reduction in risk of mortality was over two fold greater .